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KMID : 0882420090770000240
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Korean Journal of Medicine
2009 Volume.77 No. 0 p.240 ~ p.244
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A case of adult-onset Still’s disease combined with Sjogren’s syndrome
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Jung Yoon-Suk
Jung Sang-Youn
Lee Kwang-Hoon
Ha You-Jung
Baek Ji-Hyeon
Park Yong-Beom
Lee Soo-Kon
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Abstract
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Sjogren’s syndrome is a chronic, slowly progressive autoimmune disease in which the exocrine glands are damaged by lymphocytic infiltration, resulting in xerostomia and xerophthalmia. Adult-onset Still’s disease (AOSD) is a multi-systemic inflammatory disorder, characterized by a high spiking fever, an evanescent salmon-colored rash, arthralgia or arthritis, lymphadenopathy, leukocytosis, and the involvement of various organs. We report the case of a 59-year-old female patient with Sjogren’s syndrome who presented with a fever of unknown origin. She was diagnosed with AOSD based on her high spiking fever, evanescent skin rash, arthralgia, lymphadenopathy, leukocytosis, sore throat, and hyperferritinemia after extensive investigations were performed to exclude other diseases. Her AOSD symptoms were successfully treated with high-dose glucocorticoid and methotrexate, without recurrence. We describe the case of a 59-year-old female patient with Sjogren’s syndrome and AOSD.
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KEYWORD
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Sjogren’s syndrome, Adult onset, Still’s disease, Fever of unknown origin
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